Synthetic Strategies

Highlights alternative organic synthesis reactions & routes, green chemistry or cost-effective approaches

• Polar Reactions

  These reactions proceed by movement of pairs of electrons from electron-rich atoms (nucleophiles, filled orbitals) to electron-deficient atoms (electrophiles, empty orbitals). Polar mechanisms can be further divided into reactions that occur under basic conditions and reactions that occur under acidic conditions.

•  
• Free-radical Reactions

  These are reactions that occur by moving single electrons. Some free-radical reactions require electron-transfer reagents and some do not.

•  
• Pericyclic Reactions

  These reactions occur by moving electrons in a circle. The molecules involved in pericyclic reactions are usually multi-bonded (unsaturated)

•  
• Metal-Catalyzed Reactions

  These are reactions that require a transition metal, i.e. are metal-mediated reactions